As discussed above, FRAP experiments confirm that apparently stable polarized peaks are indeed maintained by very dynamic recycling of the Cdc42, Bem1, and Cdc24.
It is possible that different lineages are indeed maintained in a large area with occasional movement of viral lineages between continents, while within each area, e.g. east Asia, transmissions between borders may be still common [ 13].
A perpetual fire was indeed maintained in Hera's temple, but it had no role in the ancient Games.
The results in Figure 5F show that, in PIT exposed Teff, PD-1 is indeed maintained in the absence of further exposure to antigen.
However, at the concentrations used in this study, C6-SM did not increase the membrane permeability of a hydrophilic marker molecule (AF488-hydrazide) or a cytosolic protein (LDH), indicating that plasma membrane integrity was indeed maintained.
MacKintosh et al. [ 6] introduced the concept of "polarization memory", describing the way the initial polarization is maintained through the variation of the number of scattering events, and showed that the polarization of circularly polarized light is indeed maintained through a larger number of scattering events than that of linearly polarized light.
This hypothesis assumes that the disulfide bridge is indeed maintained throughout the lifespan of the protein; while it appears as such in the available solved structures, we note that once the protein is inside the host cell, the cytosolic environment is not conducive to disulfide bond formation.
Subsequent studies have confirmed that AML is indeed maintained by rare, specialized and phenotypically defined leukaemia propagating cells (LPCs) (Goardon et al, 2011; Hope et al, 2004), even if these populations are more diverse in phenotype than originally suggested (Taussig et al, 2010).
Consistent with earlier ATP measurements conducted in chronologically aging yeast cells (Goldberg et al., 2009), we found that intracellular ATP is indeed maintained at levels equivalent to or above those present during exponential growth for up to 5 days when cultivated under standard postmitotic growth conditions and for at least 7 days under caloric restriction conditions.
This decreased the level of constitutive activation, suggesting that negative charge repulsion was indeed maintaining the receptor in the inactive form.
