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These data strongly support that small-molecule VEGF tyrosine kinase receptor inhibitors are indeed active in tumours bearing the target, that is, endothelium with activated VEGFR2/KDR receptors.
Reprints Related items Saving: Cutting through the jungleJul 11th 2002There are indeed active managers who outperform for years.
These newsletters are indeed active traders; as of Nov. 30, for example, their recommended funds had been held for an average of only two months.
Morozov then thoroughly documents the fact that many of the three million Iranian expats are indeed active on Twitter, and that their traffic, along with sympathetic messages from non-Iranian users, made the Iranian election and its aftermath into major phenomena on Twitter.
Hence, naive p-values can persuade the user that included factors are indeed active.
The research confirms that there are indeed active volcanoes under the West Antarctic Ice Sheet, says geophysicist Donald Blankenship of the University of Texas, Austin.
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Our results show that this isoform is indeed active, associated with anion transport, and activated by Ca2+.
Although the transmission rates were significantly lower than that obtained with wild type P2, the P2-TC mutant protein was indeed active in such assays, retaining around 50% of the wild P2 activity.
The first such chimeric molecule reported, KAM1, was indeed active, like staurosporine, but was also more PKCδ-specific, and showed potent activity against Ras-mutant human cancer cells in culture and in vivo animal models, while not producing cytotoxicity in non-transformed cell lines [ 47].
And those who don't care, believing the blacklist to have been an excusable excess, might consider the following: Whereas Soviet spies were indeed active in American government and had to be exposed, Congressional "investigators" uncovered nothing in Hollywood, since every Communist there was already known.
"Ceres seems to be indeed active," he says.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com