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Protease-activated receptors (PARs) are a unique class of receptors which are implicated in mediating inflammation, pain and other functions.
Several proteins that are implicated in mediating TLR signaling attenuation have been identified such as the ubiquitin-editing protein A20 [13 15].
To date, four different PAR receptors have been identified and they are implicated in mediating inflammation and pain, among other functions [12] [14].
Coronary endothelial cells are implicated in mediating cardiac fibrosis via transmural TGF- β signaling mechanisms [ 82].
In this work, we study SET domain bearing genes that are implicated in mediating immune evasion, invasion and cytoadhesion pathways of modern apicomplexans, including malaria parasites.
Nitric oxide (NO) synthesis has been described in several circumventricular and hypothalamic structures in the central nervous system that are implicated in mediating central angiotensin-II (ANG-II) actions during water deprivation and hypovolemia.
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Oxygen free radicals have been implicated in mediating various pathological processes including burn-induced organ damage.
Kappa opioid receptor (KOR) signaling has been implicated in mediating behavioral and biochemical effects associated with drug dependence.
This tract has since been implicated in mediating the effects of at least two gastrointestinal satiety factors.
Several putative neurotransmitters and receptors have been implicated in mediating the MPR at the level of the dorsal horn.
Recently, RAGE has been implicated in mediating pulmonary arterial smooth muscle cell proliferation and vascular remodeling in experimental PH.
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