The phrase "are implicated in large" is not correct and does not convey a clear meaning in written English.
It may be intended to refer to involvement in significant issues or contexts, but it lacks clarity and completeness.
Example: "The researchers found that several factors are implicated in large-scale environmental changes."
Alternatives: "are involved in significant" or "play a role in major".
In Germany and Canada, STEC has been implicated in large outbreaks as well as in sporadic cases of hemorrhagic colitis and HUS [ 29- 31].
Viruses of lower vertebrates are abundant worldwide and have been implicated in large losses in wild fish and amphibian populations, as well as in those raised in commercial farms [ 40, 59, 62].
ISs have been implicated in large changes to genome structure, by expanding in copy number in microbial genomes, with subsequent loss of ISs resulting in inactivation of genes, pseudogene formation, mediating deletion of intervening sequences between two copies of the IS, or rearrangements of the genome [ 3].
These molecules are implicated in a large number of biological processes and human diseases (e.g., [ 2- 8]).
Furthermore, failures of these networks are implicated in a large number of neurodevelopmental disorders (e.g., Fair et al. 2010).
Autworks also allows researchers to highlight genes that belong to other sets, are implicated in a large number of other disorders.
5 Overweight and obesity are implicated in the aetiology of a large number of medical conditions.
Furthermore, variants in the vicinity of HDAC9 are implicated in causing increased risk of large vessel ischemic stroke (Bellenguez et al., 2012).
They bind RuBisCO small and large subunits and are implicated in the assembly of the enzyme oligomer.
Pentatricopeptide repeat genes form a large family and are implicated in post-transcriptional processes such as splicing, editing, processing and translation specifically in organelles such as mitochondria and chloroplasts [ 48].
