Sentence examples for are implicated in facilitating from inspiring English sources
Chemical modifications of the histone amino-terminal tails are implicated in facilitating nucleosome remodeling and repositioning, and in the recruitment of specific transcription factors.
Proteolytic enzymes have been implicated in facilitating tumor cell invasion and the current study was designed to characterize the expression of the cysteine proteinase cathepsin S (CatS) in astrocytomas and examine its potential role in invasion.
As plasminogen recruitment and the plasminogen-activated fibrinolytic system have been implicated in facilitating microbial pathogenesis, we next examined the influence of capsule formation on the cell wall surface accessibility and plasminogen binding capacity of the serotype D strains JEC21, FCH78 (cap59::nat), and FCH79 (CAP59 cap59::nat) and the serotype A isolates C23 and A1 38-2.
Indeed, neutrophils have been implicated in facilitating tumor cell extravasation.
PELP1 interacts with HER2 and is implicated in facilitating ER crosstalk with HER2 signaling pathways [ 9].
Importantly, JARID1A has been implicated in facilitating an altered chromatin state that promotes drug-tolerant subpopulations of cancer cells [ 171].
VHL has been implicated in facilitating TNF-α-induced apoptosis by suppressing the expression of NF-κB-dependent anti-apoptotic genes (Qi & Ohh, 2003).
Kallikrein proteins have also been implicated in facilitating angiogenesis via degradation of the cellular matrix [ 109] and our data showed co-regulation of Pgf and Kallikrein genes.
Integrin αvβ3 is implicated in facilitating metastasis of breast cancer cells to bone [ 55]; decreased transcription of ITGAV after MUC1 siRNA may, therefore, suggest that MUC1 is involved in this lethal process as well.
LRR-flanking cysteines have also been implicated in facilitating interactions with other proteins as in the case of mammalian TLR4 and its MD-2 (myeloid differentiation protein) partner required for the recognition of lipopolysaccharide [ 29].
Aberrant activation of K-Ras has been implicated in facilitating all aspects of a malignant phenotype, including proliferation, invasion and metastases by Ras effectors such as PIK3, Raf/MEK/ERK cascade and Rho GTPases.
