Mutations in aaRSs have been implicated in a plethora of diseases including neurological conditions, metabolic disorders and cancer.
In light of this tight regulation, it is perhaps unsurprising that dysregulation of PKC isoforms has been implicated in a plethora of cancers.
Moreover, members of the miR-17∼92 miR-17∼92ve been implicated in a plethora ofamilyerent processes, including cell cycle progression, angiogenesis, cancer, TGF- β-signaling, and lymphaveoliferative disorders.
PA is an essential signaling molecule and has been implicated in a plethora of cellular processes including cell growth, differentiation, and metastasis.
Prenylated proteins have also been implicated in a plethora of other processes, including calcium signal transduction [ 26, 27], response to heat and heavy metal stress [ 28- 30], cytokinin biosynthesis [ 31], and regulation of the cell division cycle [ 6, 32, 33].
SFK activity is inhibited by the C-terminal SRC kinase (CSK) family of tyrosine kinases [CSK and CSK homologous kinase (CHK)] (Chong et al., 2005); both CSK and CHK phosphorylate and inactivate SFKs, and mutations disrupting this activity have been implicated in a plethora of cancers.
Various factors are implicated in the formation of recurrent TEFs.
The TRIM family members are involved in a plethora of biological and physiological processes and, when altered, are implicated in many pathological conditions [ 5].
Hundreds of men are implicated in these horrific crimes.
Glycoproteins are implicated in several other allergies.
