More surprisingly, the recency influence is highly bounded to a few recently-visited locations.
Whereas geometrical space is unbounded, infinite, and homogeneous (at least in its Euclidean form), physiological space is highly bounded, finite, and non-uniform.
At the same time, these opportunities are highly circumscribed: bounded to specific interventions, targeting specific populations, and tied to short-term funding cycles and time-limited projects, they produce an 'archipelago' pattern of development (Geissler, this issue) rather than a concentric circle of progress.
Since they are highly protein-bound, all fibric acid derivatives may increase the anticoagulant effect of coumarin derivatives [ 16, 17], thus the International Normalized Ratio should be carefully monitored.
All echinocandins are highly protein-bound and have a low to moderate volume of distribution and very low excretion as unchanged drug in the urine [ 14, 16].
In malnourished patients reduced concentrations of plasma proteins may significantly increase the likelihood of toxicity from the administrations of agents that are highly protein-bound, such as prednisolone, etoposide, teniposide, cisplatin, paclitaxel and SN-38 [4].
All eukaryotic cells display a dramatic partitioning of mRNAs between the cytosol and endoplasmic reticulum (ER) compartments-mRNAs encoding secretory and integral membrane proteins are highly enriched on ER-bound ribosomes and mRNAs encoding cytoplasmic/nucleoplasmic proteins are enriched on cytosolic ribosomes.
Such high enrichment indicated that a small number of phages that specifically interact with C. albicans cells are highly represented in the bound phages.
The results show that all top motifs are highly enriched in ZNF263-bound regions with respective p-values of 2.35e-57, 3.80e-19 and 9.01e-3 9.01e-3lidation in Materialseend methods).
They are highly reactive with weakly-bound electrons rich in the more reduced intracellular/intranuclear environment of cancer cells.
