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Frameshift mutagenesis by benzo[ a]pyrene lesions requires both pol II and pol V whereas frameshifts are generated uniquely by pol II for N-2-acetylaminofluorene (38, 39).
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Therefore, some hemoglobin cleavages appeared to be generated uniquely by proteases other than the falcipains.
Hedonic components of 'liking' reactions to pleasant sensations and 'disliking' reactions to unpleasant ones may be generated uniquely by subcortical inputs to the hedonic generating keyboard for amino acid signals in medial shell, such as collaterals from neighboring intrinsic neurons, accumbens-pallidal loops, brainstem inputs and related projections [67], [68], [69], [70], [71], [72].
Interestingly, a novel form of Jo-1 that is more susceptible to cleavage by granzyme B in the human lung has been demonstrated [ 35], raising the possibility that novel Jo-1 cleavage fragments might be generated uniquely in the lung.
The shallow water waves that drive the tsunami inundation flows described in this paper are generated using a novel tsunami simulator, uniquely capable of generating very long period waves featuring the characteristic draw-down of real-world tsunami.
Its visuals and sounds are generated and animated live, offering a uniquely different performance for each and every iteration.
It reveals that the different algorithms produce different sets of clusters: around 85% of clusters are uniquely generated by a single algorithm, 7% of clusters are generated by two algorithms, and the remaining 8% of clusters are generated by three or more algorithms.
To visualize the reads along the fission yeast genome, wiggle files were generated from uniquely mapped reads based on their location and counts.
'bedGraph' files were generated from these uniquely-mapped, non-duplicated, extended reads for visualization of aggregate genomic coverage.
Methylation profiles were generated from non-redundant uniquely mapping reads ('Material and methods').
A total of 2.38 and 2.21 billion uniquely mappable reads were generated from germline and tumor DNA, which equates to 108 Gb and 100 Gb of uniquely mappable sequence for germline and tumor, respectively.
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