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The phrase "are generally considerable" is correct and usable in written English.
It can be used when discussing the significance or importance of something in a general context.
Example: "The costs associated with the project are generally considerable, impacting the overall budget significantly."
Alternatives: "are usually substantial" or "tend to be significant."
Exact(1)
Despite some evidence of ameliorated glycemic control (3) and inflammatory biomarkers (3, 4) after improvement in vitamin D status, vitamin D supplementations have not resulted in improvement of glycemic or metabolic status in some populations, and interindividual variations in response to vitamin D intake are generally considerable (5).
Similar(59)
And there is generally considerable public support for redistricting reforms whenever they are on the ballot.
Although this yields useful insights, there is generally considerable environmental variability and uncertainty within the system.
There is generally considerable uncertainty in the inference of a phylogenetic tree.
States and local school boards are generally afforded considerable discretion in operating public schools.
Modeled niches are generally conservative over considerable time periods [ 20, 21], offering considerable predictive power regarding distributional ecology of species, including when environmental conditions are changing [ 8, 22].
Goods such as subsidized housing or social services, which predominantly help the poor, or health care services, which help the poor and elderly, are generally regarded as having considerable merit and therefore have a strong claim on government resources.
In addition, the results obtained are generally affected by a considerable degree of uncertainty; cross tests using different techniques make it possible to improve the quality of the diagnosis.
Thus in the much studied "ultimatum game", subjects are generally willing to incur considerable costs to punish unfair behavior (Oosterbeek, Sloof and van de Kuilen 2004).
The latter (2-3% of the population) are generally unemployed, and need considerable help in many bio-psycho-social areas on a long term basis (Nelson 2006).
Potbelly sculptures are generally rough sculptures that show considerable variation in size and the position of the limbs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com