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These functions are fundamental for normal fetal development and delivery.
The nucleocytoplasmic trafficking pathways are fundamental for normal cell functions as well as plant defense responses [ 34].
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Discerning facial emotions is fundamental for normal social interaction and commences in early infancy [ 1].
The R-point is fundamental for normal differentiation and appears to be dysregulated in virtually all cancers.
DOI: http://dx.doi.org/10.7554/eLife.06535.002 The proper control of eukaryotic gene expression is fundamental for normal development and cellular response to environmental challenges.
In parallel, expression of the H3K4 demethylase Rbr-2 is also required for normal worm longevity, suggesting that maintenance of a H3K4 methylation level is fundamental for normal aging (Greer et al., 2010).
As DG is involved in the development of basement membranes, it certainly is fundamental for normal human development, and the failure to identify null mutations in DAG1 linked to muscular dystrophies in humans is probably due to early embryonic lethality of such mutations.
As mentioned in the introduction, ROS are fundamental for the normal functioning of the thyroid follicular cell.
Amino acids are fundamental for the normal growth and development of the early embryo, acting as precursors of nucleic acids and proteins, osmolytes and signaling molecules.
Interactions between TEC and developing thymocytes, named "thymic crosstalk" [6], are fundamental for the development of a normal thymic architecture [7], [8], [9].
Normals and curvatures are fundamental for geometric modeling and computer-aided design, but their accurate computations on discrete surfaces are challenging.
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CEO of Professional Science Editing for Scientists @ prosciediting.com