The phrase "are functionally active in" is correct and usable in written English.
It can be used to describe the active role or involvement of something in a particular function or process.
Example: "The enzymes are functionally active in the metabolic pathways that convert food into energy."
Alternatives: "are actively involved in" or "play a functional role in".
Both the longer and shorter isoforms contain the major functional domains of the protein, including the GTPase domain, and are functionally active in biochemical assays [ 29, 36].
While the DNA in cells encodes for somewhere between 20,000 and 35,000 genes, only a fraction of these genes are functionally active in any given cell type.
These immune cells are functionally active in the adipose tissues and produce numerous cytokines and other regulatory factors that influence endocrine and lipid metabolism [32], [33].
Clearly, as evidenced by our data, we confirm the results of others [17], [18], [19] that NFκB genes are functionally active in undifferentiated hESC but the TLR4 PAMP is unable to produce a NFκB translocation in these cells.
This method allows transcription factors that are functionally active in gene expression to be investigated.
This experiment indicated that the cloned porcine MSTN gene regulatory elements are functionally active in a mammalian cellular context.
Alternatively, elevated circulating lyso-PCs may not be functionally active in this process but represent activated pathways in the synthesis or metabolism of phospholipids and phosphatidylcholine and, thus, in the generation of hepatic endoplasmic reticulum stress (40) (Supplementary Fig. 2).
Consistent with this localization, TLR2 is functionally active in synovial fibroblasts and endothelial cells, where its activation results in induction of VEGF, IL-8, ICAM-1, VCAM-1 and MMPs [ 15, 21, 22, 27- 29].
Relatively low cell adhesion was observed on uncoated collagen nanofibers, whereas collagen nanofibrous matrices treated with type I collagen or laminin were functionally active in responses in normal human keratinocytes.
It was found that nanofibrous membranes made of PLGA/collagen were functionally active in responses in human fibroblasts, and were very effective as wound-healing accelerators in early-stage wound healing.
The purified proteins were functionally active in flow cytometry, immunofluorescent microscopy, and competition binding experiments performed to delineate the epitopes recognized by different monoclonal antibodies against the same polypeptide.
