However, in ICU patients with coexisting illnesses, such as those with acute respiratory distress syndrome or chronic obstructive pulmonary disease, the response to mechanical ventilation is frequently unpredictable [ 6].
The goal of the first method is to treat haemorrhoidal prolapse by resecting the rectal mucosa approximately 3 4 cm above the dentate line 18; however, the level of anastomosis is frequently unpredictable as it is affected by the traction applied to the previously performed rectal purse-string.
Apparently 'simple' interventions are frequently complex and unpredictable in their effects (Read et al. 2011; Derde et al. 2014; McVicker et al. 2014; Nicolle 2014).
While CRISPR-Cas9 thus enables predesigned modifications of the genome, applications of CRISPR-Cas9-mediated genome-editing are frequently hampered by the unpredictable and varying pathways for DSB repair in mammalian cells.
Unpredictable systems are frequently handled with the methods of probability theory and termed stochastic.
In addition, the antibodies isolated via human cell screening should express efficiently in mammalian cell systems, without the unpredictable problems that are frequently seen in expression of antibodies selected by phage display.
Illness is often unpredictable.
It is often unpredictable.
