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Tumors with these mutations are frequently sensitive to tyrosine kinase inhibitors (TKIs).
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Leukemia cells were chosen in this study for initial screenings, because leukemia cells are frequently more sensitive to cytotoxic agents than most other tumor types.
This observation is in accordance with the clinical situation, as it is well known that hematological tumors cells are frequently more sensitive than solid cancers [ 14].
Often this is not the case, indeed the opposite can hold true, cancer cells are frequently more sensitive than normal tissue to therapy-induced apoptosis.
In more than two thirds of these women, tumours express either oestrogen receptors (ERs) or progesterone receptors (PgRs), which are frequently less sensitive to chemotherapy (EBCTCG, 2005), but are amenable to hormonal therapy.
As a consequence, lichens are frequently used as sensitive indicators of environmental change.
Lawyers for the Justice Department are frequently involved in highly sensitive litigation, drawing on documents that while not classified, would typically be kept confidential.
Soils with high organic content are frequently encountered beneath earthquake sensitive infrastructure, such as bridges or levees.
Pruritus and sensorial irritation (sensitive skin) are frequently reported.
Automatic alarms can clearly be beneficial, although it is a common observation that highly sensitive alarms are frequently ignored due to their relatively low specificity [ 9].
The study utilized a capsulated nontoxinogenic strain of B. anthracis; however, for safety reasons toxinogenic noncapsulated strains are frequently used in combination with sensitive mouse strains.
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