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The phrase "are frequently large" is correct and usable in written English.
It can be used to describe something that often has a significant size or magnitude.
Example: "The data sets we analyze are frequently large, requiring substantial computational resources."
Alternatives: "are often substantial" or "tend to be considerable".
Exact(7)
However, in autonomous navigation tasks, the state spaces are frequently large and demonstrations can hardly visit all the states.
Because they are frequently large enough to contain an entire gene and its associated regulatory elements, BACs can serve as a source of gene-specific promoter sequences.
On imaging villous adenoma are frequently large with flat carpet like or cauliflower/frond like appearance (Figs. 2 and 3).
Due to the large potential space within the retroperitoneum, and late non-specific symptoms of retroperitoneal sarcomas, they are frequently large at the time of diagnosis.
They have tumours that are frequently large, involve the regional lymph nodes or extend beyond the breast tissue [ 12].
Phyllodes tumors are frequently large and occasionally reach up to 30-40 cm in diameter [6]– [9].
Similar(53)
Now experiments are frequently larger than a city block, and experimental physicists lead very different lives - programming computers, working with industry, co-ordinating vast teams of scientists and engineers, and playing politics.
The CellSieve™ technique uses size discrimination to separate and isolate cells, and thus may be useful for capturing CTCs that are frequently larger than white blood cells [14].
MuTIR sequences are expected to be absent from a proportion of FSTs, because the MuTAIL products were cloned in random orientations and are frequently larger than single-pass sequence reads.
Champagne buckets are frequently larger than other wine chilling buckets to allow for more water and ice.
The writing is frequently large, especially in the early examples, so that there may be as few as three lines to a single page.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com