Based on the original two-dimensional version in [4], the surrogate models have been frequently improved within the last years.
For a period in the early 18th century, castles were shunned in favour of Palladian architecture, until they re-emerged as an important cultural and social feature of England, Wales and Scotland and were frequently "improved" during the 18th and 19th centuries.
Prospective home buyers are frequently advised to improve their credit scores before applying for a mortgage.
Lipid layers are frequently used to improve the stability and biocompatibility of nanoparticles.
RNA and cDNA fragmentation are frequently used to improve evenness of coverage across the length of transcripts so splice junctions and SNPs can be more efficiently detected.
Thus, high data densities are frequently used to improve curve fitting precision (Fig. 1).
Diuretic agents are frequently used to improve urine output and to facilitate fluid management in these patients.
Oliguria is a poor prognostic indicator in patients with AKI [ 15, 16], and diuretic agents are frequently used to improve urine output and to facilitate fluid management in these patients.
Consequently, when older adults are seen by their medical providers at an interval of 3 to 6 months, small changes made during clinic visits are frequently inadequate to improve overall glycemia.
Multiple gene copies are frequently found to improve protein production [ 24], even though increasing copy numbers does not necessarily raise expression due to reasons such as saturation of transcription factors or pleiotropic effects of random integrations [ 3, 25].
Pharmacological strategies, as antibiotic prophylaxis, antiemetics etc. are frequently prescribed to improve tolerance to the planned chemotherapy treatment, and now physical activity in recent years has been used as a strategy for rehabilitation in cancer patients to remedy disease and treatment related symptoms and side effects.
