Even though B. anthracis is sensitive to different antibiotics, their therapeutic benefit is frequently diminished by the late onset of symptoms.
Consequently, apoptosis is frequently diminished in cancer cells, supposedly caused by a dominance of anti-apoptotic proteins in malignant tumours.
Although p27 function is rarely disrupted at the genetic level, it is frequently diminished in human cancers because of accelerated proteolysis, sequestration by other proteins, and cytoplasmic mislocalization.
In this study, we demonstrated that expression of HOXB13 is frequently diminished in colorectal tumours to confer a positive growth signal, which may be accomplished thorough the regulation of β-catenin/TCF4 signals.
On the basis of their expression array analysis of chromosome 8p11 21 genes, Ugolini et al (1999) reported that expression of SFRP1 mRNA is frequently diminished or lost in breast carcinomas, and they also found that loss of SFRP1 occurs in more than 80% of invasive breast carcinomas, although not in the medullary type (Ugolini et al, 2001).
Perhaps unsurprisingly, health related quality of life (QOL) and activities of daily living (ADL) are frequently significantly diminished [ 5- 12].
The fact that lifeguard positions are frequently filled by teenagers does not diminish this responsibility: these teenagers have taken it upon themselves to -- well, actually guard lives.
The fact that joint counts are frequently not assessed routinely does not diminish these notions; deletion of joint counts from composite scores cannot be justified for a disease of the joints, and joint counts can always be performed at the time of patient visit to the clinic by the physician or another assessor.
Traditional treatments for cancer, such as radiation and chemotherapy, are frequently ineffective and are often associated with painful side effects that diminish the quality of life for patients.
Patients with lateral epicondylitis (tennis elbow) are frequently treated with corticosteroid injections, in order to relieve pain and diminish disability.
All are frequently updated.
