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Most interactions are found in the biosynthesis of ergosterol, ubiquinone, sphingolipid and glucogen synthesis (Additional File 3).
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Other anaerobic to aerobic transitions may also be found in the biosynthesis of BChls in Cfl.
For instance, a large fraction of the BIOMASS modifications (8/10) were found in the biosynthesis of polysaccharides.
The genes neuA and neuB are found in the LPS biosynthesis gene clusters of several Gram-negative species.
Among the 256 COGs found by the purine biosynthesis query, seven COGs that belong to the pyrimidine biosynthesis are found in the first iteration.
One example of this diversity is found in the B12 biosynthesis pathway.
The highest number of transcripts (1,422) was found in the secondary metabolites biosynthesis pathway (Table 1).
Among these, FAA2 and FAA1 were successfully captured by MESSI in the top 3 in target pathway 'Fatty acid biosynthesis', and POX1 was found in the top-3 in correlated pathway 'Biosynthesis of unsaturated fatty acids'.
However, a tabtoxin biosynthesis gene cluster is found in the Pta 11528 genome and shows a high degree of conservation with the previously sequenced Pta BR2 tabtoxin biosynthesis cluster [ 69].
Limonene is an interesting case, which implies that genetic information drives the biosynthesis of the enantiomers, the dextrorotatory d-limonene is found in the orange or lemon peel.
The AC cis-regulatory elements, for example, which are found in many promoters of phenylpropanoid and lignin biosynthesis genes, play an important role in gene regulation in lignifying xylem cells, thus linking R2R3-MYB genes with lignin biosynthesis.
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