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The two current approaches to the analysis of antibody repertoires [next generation sequencing (NGS) and mass spectrometry (MS)] present difficult computational challenges since antibodies are not directly encoded in the germline but are extensively diversified by somatic recombination and hypermutations.
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The former belongs to a more recently-diverged group (pennates), thought to be extensively diversified by the acquisition of exogenous genes, and by rearrangements mediated by the retrotransposon elements prevalent in the genome [ 67].
Second, kakapo are extensively managed.
Whitefish (Coregonus spp., Fig. 1J) are one of the most extensively diversified fish in large and deep lakes of the Northern Hemisphere (Turgeon and Bernatchez 2003; Hudson et al. 2011).
An analogous case is the extinct clades of Palaeochiropterygidae and Hassianycteridae, which extensively diversified in Central Europe during geographic isolation of that region in the Early and Middle Eocene [ 43, 44].
While the diversifying role of sexual selection in shaping courtship behaviour has been extensively studied, the role of evolutionary constraints has gained less attention [ 17, 21- 23].
Although the pattern and process of host switching in the terrestrial ecosystem have been extensively studied, most notably in herbivore insects [ 9], little is known about how symbiotic marine organisms expand their host ranges and diversify via host switching.
Property was extensively nationalized.
Stations are being extensively rebuilt.
Market gardening is extensively practiced.
This has been extensively demonstrated.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com