Sentence examples for are extensive changes from inspiring English sources

Our results indicate that there are extensive changes in gene expression in all regions of the brain examined.

Concomitant with germ cell specification and proliferation are extensive changes in the epigenetic state of these cells.

There have been extensive changes at Le Cirque since 2006, and the quality of its French-Italian food has improved.

Since then there have been extensive changes, most notably the arrival of a new executive chef, Christophe Bellanca, in place of Pierre Schaedelin.

Brian Lightman, general secretary of the Association of School and College Leaders, said: "There have been extensive changes to initial teacher training in recent years with the introduction of School Direct, and we know there have been issues with shortages in some key subjects.

It would involve far more than just higher levees: there would have to be extensive changes to the city's system of drainage canals and pumps, environmental restoration on a vast scale to replenish buffering wetlands and barrier islands, and even sea gates far out of town near the Gulf of Mexico.

The proposals have yet to be finalised but there will be extensive changes to constituencies across the UK if the plans go ahead.

The home's owners, Castlebeck, said there had been "extensive changes in board and management" and new measures introduced to ensure it could not happen again.

Following the public outcry since 2012 about the more serious forms of these offenses, there have been extensive changes in the Indian Penal Codes in distinguishing sexual harassment behaviors.

Certainly there can be extensive changes in gross biochemical composition as cultures are starved.

There were extensive changes in the expression of genes involved in many different metabolic pathways in the WAT of FSP27-deficient mice.