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The phrase "are exceptionally refractory to" is correct and usable in written English.
It can be used in contexts where you want to describe something that is resistant or unresponsive to a particular influence or treatment.
Example: "The materials used in the construction are exceptionally refractory to high temperatures, ensuring durability and safety."
Alternatives: "are highly resistant to" or "are particularly unresponsive to".
Exact(1)
Significantly, quiescent cancer stem cells have been identified, which are exceptionally refractory to cytotoxic treatments (44) and oxidative stress damage (45, 46) and are slow-cycling, label-retaining cells with high clonogenic capacity and tumorigenicity (47).
Similar(59)
Accordingly, it is possible to link GE to a rifamycin to construct a bipartite inhibitor that binds simultaneously to the GE target and the rifamycin target and, therefore, that is exceptionally potent and exceptionally refractory to target-based resistance.
Certain writers are exceptionally difficult to translate.
They are exceptionally hard to see.
Cyclotides are exceptionally resistant to thermal and biochemical extremes and to treatment with endoproteases [ 7].
It has been found that [ 8] diabetic patients are exceptionally susceptible to sinusitis infections.
The cut indices values of woven fabrics are exceptionally high in contrast to knitted fabrics.
I am speaking to people who are exceptionally bright.
It's exceptionally easy to make.
"That's exceptionally difficult to do.
That is exceptionally hard to arrange.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com