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Thus, the numbers and distributions of the three major lung epithelial cell types are established by two distinct Notch-dependent mechanisms: Notch2 signaling controls Clara cell number, and three Notch receptors in SPNC cells activate Hes1 to control pNEBs.
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DNA methylation patterns in mammalian cells are established by three main DNA metyltransferases (DNMTs).
The model is established by two steps.
(4) Any other entity which is established by two or more of the entities described in paragraph (k)(1), (2), or (3) of this section.
Id. at 4. Novartis appealed, arguing that the validity had been established by two federal courts, the Federal Circuit and the District Court for the District of Delaware.
They hired not only MacKenzie but also the same landscape-architecture firm that Hollins had used to create her real-estate development plan: Olmsted Brothers, which had been established by two sons of the creator of Central Park.
The khanates of Bukhara and Khiva (Khwārezm) were established by two branches of the Shaybānid dynasty, which won control of Transoxania from the Timurids in the late 15th and early 16th centuries.
But his preeminence among non-Italian composers of opera was established by two one-act operas, both shocking in their time: Salome (1905; libretto taken from Oscar Wilde's drama, translated into German by Hedwig Lachmann) and Elektra (1909).
A precedent was established by two European member states, Britain and France, showing a willingness to take both the diplomatic and military lead, albeit with vital (if slightly grudging) support from America.
By the end of that day the September 11th Fund had been established by two major local charities.
As a result, a 2-D parameter space, in which motion states were visualized and identified, was established by two components of velocity to define the motion states (see Figs. 2K and 3D).
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CEO of Professional Science Editing for Scientists @ prosciediting.com