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The phrase "are drastically different in" is correct and usable in written English.
It can be used to compare two or more subjects that exhibit significant differences in a particular aspect or characteristic.
Example: "The two cultures are drastically different in their approaches to family values."
Alternatives: "are significantly different in" or "differ greatly in".
Exact(12)
They are drastically different in their targets of improvement, visibility, and techniques.
The free energies calculated using a continuum solvation model show that the lowest free energy conformations, while being energetically equal, are drastically different in conformations.
The Ohio State and the Southern California cases are drastically different in nature, but they intersect in a place where big-time college athletics appear to be spiraling out of control.
Though the two regions are drastically different in climate and wine style – one a hot region for sweet, fortified wines, the other a cool-climate producer of sparkling – they actually have quite a few similarities.
However, the nuclear division cycles and Bcd gradient preceding precise patterning are drastically different in comparison to embryos developing under normal conditions.
Only two oxidative forms Cr III and Cr VI are stable enough to occur naturally, but they are drastically different in charge, physiochemical properties as well as chemical and biochemical reactivity (Kotas and Stasicka, 2000).
Similar(48)
Although they were drastically different in price, they seemed to have the same features.
The market can be drastically different in other parts of the country.
But while it may be useful to draw some comparisons to the U.S. subprime debacle, India's experience is drastically different in significant ways.
Warren Beatty's new film, "Rules Don't Apply," set mainly in 1959 and framed by a sequence that takes place in 1964, is two movies in one, and they're drastically different in tone, substance, and affect.
But my point here is that, to Adams and to many others, you're not supposed to look at history at this sort of golden, perfect moment that's drastically different, in that sense, from everything since.
More suggestions(13)
are radically different in
are greatly different in
are distinctly different in
are significantly different in
are tremendously different in
are sharply different in
are enormously different in
are markedly different in
are noticeably different in
are considerably different in
are drastically dissimilar in
are fundamentally different in
are vastly different in
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com