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The phrase "are drastically different and" is correct and usable in written English.
It can be used to compare two or more subjects that have significant differences.
Example: "The two proposals are drastically different and require separate evaluations."
Alternatives: "are significantly different and" or "differ greatly and".
Exact(2)
"I don't think there is room for both unless they are DRASTICALLY different and publishers find new ways to monetize the players," Sundberg said.
The calories in these types of food are drastically different and can lead to either malnutrition, in the case of the kitten eating adult food, or excess weight, in the case of the adult cat eating kitten food.
Similar(58)
The developed methods are fully conservative, and used to compute a variety of multi-component flow problems, where the equations of state can be drastically different and stiff.
Our workforce of today is drastically different and we cannot begin to imagine what our current students will need to be able to do in the future.
After this initial phase, the response is drastically different and shows reverberating activation of the different layers lingering well beyond the offset of the input.
In reality, these different cell types at different positions in the genealogy should not be drastically different, and one should expect that samples from closely related types may offer additional information to the cell type in question.
The histogram for the Gsk3 mutants in Figure 2 is drastically different and reflects the distribution of Cux 1 neurons observed by inspection in many additional Gsk3 Neurod6 and Gsk3 loxp :Neurod6 mice.
Though we could not analyze the diversity of cloning efficiency between rice and Arabidopsis because the numbers of FL-cDNA clones are drastically different between rice and Arabidopsis (580K and 27K, respectively (http://signal.salk.edu/)), we could not find the diversity of cloning efficiency by organisms (Table S5a and b).
Though the two regions are drastically different in climate and wine style – one a hot region for sweet, fortified wines, the other a cool-climate producer of sparkling – they actually have quite a few similarities.
Using more than 150 MIP proteins, Froger et al. [ 58] identified five positions (P1-P5) where the physicochemical properties of the corresponding amino acids are drastically different in aquaporins and glycerol permeases.
The age of two important percomorph clades, the cichlids and the tetraodontiforms, are drastically different between our study and previous work [ 10, 11] (Fig. 3).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com