The phrase "are dramatically upregulated in" is correct and usable in written English.
It is typically used in scientific or technical contexts to describe an increase in the expression of genes or proteins in a specific condition or environment.
Example: "In response to stress, certain genes are dramatically upregulated in the affected cells, leading to enhanced survival mechanisms."
Alternatives: "are significantly increased in" or "are markedly elevated in".
Indeed, these parasitic elements are dramatically upregulated in KAP1- and SETDB1-deficient mESCs [ 24, 28].
To examine the clinical significance of these responses, the authors found that both TLR4 and HSP70 are dramatically upregulated in damaged tubules of kidneys from individuals with DN.
Intriguingly, these families are dramatically upregulated in SETDB1 knockout (SETDB1 KO) mESCs [ 19, 20], confirming that they have a high potential for activation in the absence of H3K9me3.
When we tested the top 402 genes from the microarray list of vasculitis-upregulated genes (data not shown) by RT PCR, we identified 63 genes whose expression levels are dramatically upregulated in vasculitis patient PBMCs (Fig. 4).
In particular, TF is dramatically upregulated in a transformed murine breast epithelial cell line (EMT6) under these conditions.
Type VIII collagen, a short chain collagen, is scarcely present in normal arteries, but is dramatically upregulated in atherosclerosis and after other types of vascular injury.
When transferred from seawater (30‰) to 40‰ sea water, the expression levels of Tonkcc1a mRNA were dramatically upregulated in gills and intestine compared to that in the control.
The ethylene signaling pathway was also activated under heat stress in TM-1, as nine each of the genes encoding ethylene receptors and ethylene response factors (ERFs) were dramatically upregulated in TM-1 (Fig. 5b,c, Supplementary Fig. 23c and Supplementary Tables 41 and 45), elucidating their role in regulating EIN3 and EIL1 activation under heat stress53.
HBD-2 induction was dramatically upregulated in the presence of SB216763 and FSL-1.
We have revealed here a number of novel findings for the PCA3 biomarker gene that is dramatically upregulated in PCa.
