Sentence examples for are directly activated from inspiring English sources

ADFs/cofilins activities are directly activated by Slingshot phosphatase (SSH) [24] and inhibited by LIM kinase (LIMK) by dephosphorylation and phosphorylation on the N terminal serine 3 residue, respectively [25], [26].

It was previously shown that TRPC3, TRPC6 and TRPC7 are directly activated by DAG, which clearly explained the activation of these channels upon ligand activation of Gq-coupled GPCRs (Hofmann et al, 1999).

Another possibility is that neurotensin induces Akt phosphorylation through activation of subtypes of PI3K that are directly activated by GPCRs [ 66, 67].

Whereas TLR receptors are directly activated by versatile microbial ligands, Drosophila Toll-1 receptor activation is dependent of the maturation of its Spätzle ligand by proteolytic cleavage [18], [61], [62].

One candidate pathway is that of STAT (signal transducer and activator of transcription) proteins, a subset of which are directly activated by EGFR independent of JAK signalling or bridging (David et al, 1996).

The activation of T lymphocytes depends on interactions with professional antigen-presenting cells (APCs), specialized cells of the innate immune system that are directly activated by the pathogens they engulf and regurgitate for presentation to, and activation of, T cells.

In the model, p38 phosphorylation was assumed to be directly activated by enzymatically active caspase-8 (Supplementary Figure S8).

This protein is directly activated by ARA, but DHA also serves as an activator of STX3.

In this paper, we show that RhoA can be directly activated by ROS in cells and that ROS-mediated activation of RhoA can induce cytoskeletal rearrangement.

Signal transducer and activator of transcription 1 (STable Table 1, #23) is directly activated by ROS in the brain.

In sharp contrast, if Rac GTPase could be directly activated by mechanical forces at the cell surface, then its activation would not depend on Src activity.