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MAD-LEEM is designed for the purpose of imaging biological and insulating specimens, which are difficult to image with conventional LEEM, Low-Voltage SEM, and TEM instruments.
Finally, fossils hosted in a compositionally similar matrix are difficult to image using CT because they lack substantial density contrast.
Currently embryonic stem cells (ESCs) can differentiate into articular cartilage by forming aggregates (embryoid body (EB), pellet, micromass), which are difficult to image.
Due to their anisotropic shape the subunits are difficult to image at high resolution by cryo-EM.
These genetically driven models, while superior in providing a more accurate reflection of natural tumor development and behavior, are difficult to image in the laboratory using existing techniques and technology.
As noted above, these individuals are difficult to image, and therefore, equivocal findings may have been reported as positive, lowering PPV.
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So while it is difficult to image a nanocluster in the imaging mode, SAED measurements can be useful for the analysis.
With currently available imaging technologies, it is difficult to image the fine moving structures such as valve leaflets and chordae tendinae with the image quality sufficient enough for 3D printing.
It is difficult to image deep into cells with single-molecule imaging techniques.
It is difficult to image anyone less suited to the role.
In the intervening 25 years, her influence on recorded music has been huge – it's difficult to image Tori Amos, Björk, even Lady Gaga without her.
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