Sentence examples for are difficult to formulate from inspiring English sources

Most invitees understand that guest lists are difficult to formulate, and that budgets, venues and large families can force tough choices.

Additional numerical examples are presented for which analytical methods are difficult to formulate and do not exist in the literature, in order to bring out the breadth of application of the finite element method.

Valid explanations for the difference of efficacy of idraparinux after a DVT and a PE are difficult to formulate.

PLGA particles are particularly useful for agents that have low solubility in water, and therefore are difficult to formulate as drugs.

A priori expectations of the values and distributions of genetic correlations are difficult to formulate (Price and Schluter 1991; Roff 1996).

Chemotherapy relies heavily on small therapeutic compounds, many of which are difficult to formulate and administer or suffer from biodistribution problems.

β-carotene was used as a poorly water-soluble model substance that is difficult to formulate with conventional solid dispersion formulations.

Intelligibility varies so much with the speaker and the hearer, however, that it is difficult to formulate firm criteria on that basis.

It did not take Arthur long to discover that it is difficult to formulate a useful model in conventional mathematical terms.

It is difficult to formulate a distinct definition for each of these terms, because their use largely overlaps in the literature despite individual preferences.

But it is difficult to formulate the reductionist claim precisely.