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Cognizant of the fact that clear labeled projecting fibers using aged human brain tissue are difficult to demonstrate with small amounts of crystal, we ventured to see whether the usage of a relatively larger deposit combined with a very lengthy incubation interval (seven years) would enable us to demonstrate the projecting tracts of the adult human red nucleus.
In fact, the differential effects of IFNα and IFNβ are difficult to demonstrate.
Survival gradients in combined leukaemias are difficult to demonstrate, probably because they are not a homogenous group of diseases.
Results of the few epidemiologic studies conducted on this topic (32 – 35 ) were rarely conclusive but such associations are difficult to demonstrate with observational data.
Although they should not be ignored, these concepts are difficult to demonstrate scientifically and even more difficult to quantify in terms of their ecologic importance for virus persistence.
The pathways linking globalization, health and health inequalities are complex; they are difficult to demonstrate and not well understood [ 1, 2].
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"It was difficult to demonstrate how this was applicable to human welfare," said Fields.
But the armpit effect has been difficult to demonstrate and some experts dismissed it as impossible.
"Hard evidence for effects in humans is difficult to demonstrate, though there are some exceptions," he said.
And because the business had been part of a larger operation, its financial performance was difficult to demonstrate.
Federal authorities largely rely on local enforcement of the law, and non-enforcement is difficult to demonstrate.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com