Sentence examples for are difficult to align from inspiring English sources

Moreover, conserved regions with ICS are difficult to align well by one single alignment.

Traditional internal alignment accuracy decreases as evolutionary distance increases; different sequences are difficult to align accurately.

Problematic sequences that are difficult to align or result in extraordinarily long branches were excluded from the individual unmasked alignments and all single protein datasets were re-aligned with MAFFT and masked using ALISCORE.

These repeats typically generate regions in the alignment with high variability in sequence and length, and that are difficult to align.

However, at present, the analysis of next-generation sequencing data is challenging, in particular because most sequencing platforms provide short reads, which are difficult to align and assemble.

Similar to small tumors, LN PET images are difficult to align perfectly with CT images that often have poor soft tissue contrast.

Some sequences, particularly ribosomal genes such as 18S, are known to be difficult to align properly [ 98], and these alignment ambiguities can significantly affect phylogeny reconstruction [ 95, 99].

From the perspective of land plant alignments, matK is also problematic, as it was difficult to align seed plants with other land plants (e.g., the seed plant alignment took about two person days to complete and carefully check for the current small sample of taxa).

For example, the In 2L t proximal break point in D. melanogaster and D. simulans shows a large number of indel polymorphisms at the break point (Andolfatto and Kreitman 2000) and similar results are found for the In 3R P break point (Matzkin et al. 2005), suggesting that reads from such a rearrangement break point would be difficult to align to the reference with current-generation aligners.

Alignment of the TCP and R domains is unambiguous across taxa, however, the intervening region is difficult to align; therefore, we omitted ambiguous portions of this region from the alignment.

That is because it is difficult to align the interests of people who live in forests (now 20m in the Brazilian Amazon) with those of the rest of humanity.The best way of doing so involves a mixture of two ideas: establishing clear property rights over land and paying its owners not to cut down trees.