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The phrase "are different in that while" is correct and usable in written English.
It can be used to compare two or more subjects, highlighting their differences in a specific context.
Example: "Cats and dogs are different in that while cats are generally more independent, dogs tend to be more social and loyal."
Alternatives: "differ in that whereas" or "are distinct in that although".
Similar(60)
Here the most marked feature was that while inner retinal vessels accumulate Aβ in a patchy progressive manner along their length, choroidal vessels were different in that some accumulate Aβ deposits while others seem to remain Aβ free.
The detection of unilateral components in mice compared to bilateral components for the same networks in rats indicate that the LFF of left and right cortices are different in mice while being similar in rats.
Of these, fifteen regions are different in FTNF002-00, while 18 are different in OSU18, and 9 in LVS.
However, trends are different in each typology; while richness is stable in alpine lakes, it drops for coastal lagoons, ponds and karstic lakes.
In contrast to this view, many philosophers have argued that while humans are different in a variety of ways from each other and other animals, these differences do not provide a philosophical defense for denying non-human animals moral consideration.
White codes are different in their cost from yellow/red, while green over-run both categories.
While all of them are different in certain aspects, they can be summarized by the fact that they are bystanders instead of workers.
And while those numbers are different in N.C., where about a fourth of voters support gay marriage, tolerance is growing.
While all people are different, in some respects, we share the same cognitive and emotional repertoires.
I don't know how things would be different in Kansas City, because it has been a while since sports fans lived there.
Among our four sites, Japan, South Korea and Taiwan are high-income countries, while China is different in terms of health care resources, health financing and people's socio-economic status.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com