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Ultimately, empirical testing and evidence are determinative for scientific truth claims.
Both alternative and constitutive exons are recognized by multiple weak protein:RNA interactions and different exons differ in the interactions which are determinative for exon usage.
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Luther's Small Catechism also enjoys official status in all Lutheran churches and has been determinative for most Lutheran preaching and instruction.
A third factor which is determinative for the seriousness of the injury is the volume.
Indeed, individuals differ according to their prior knowledge, the latter being determinative for their ability to detect and make sense of information.
As one can see, this planar approach was determinative for choosing the base pairs self-assembly types that have been observed experimentally [8].
Their alkylation may cause changes in the cellular architecture and, in direct line with that, be determinative for the onset of vesication.
It follows that information disclosure is also dependent upon the type of innovation at stake, the latter being determinative for the allocation of property rights among agents (Aghion and Tirole 1994) and the selection of the fittest appropriation regime for capturing and sharing the value generated by the commercialisation of innovations.
CELF activity may therefore be determinative for inclusion of an exon in heart, but not in skeletal muscle.
In the heart, a recent study found that nearly half of transcripts that undergo fetal-to-adult alternative splicing transitions in mice respond to over-expression of CELF1, suggesting that the level of CELF activity is determinative for alternative splicing of these transcripts in heart [4].
Further, the weak association between DNA damage and age found in this meta-analysis raises the question of if accumulation of damage is determinative for the aging process.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com