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pH-sensitive liposomes are designed to undergo acid-triggered destabilization.
Such molecules are designed to undergo metabolic inactivation when entering circulation, thereby limiting systemic exposure and reducing the risk for side effects.
Cell-encapsulating hydrogels used in regenerative medicine are designed to undergo a rapid liquid-to-solid phase transition in the presence of cells and tissues so as to maximize crosslinking and minimize cell toxicity.
Our results suggest that the neural networks that support working memory operations have different temporal dynamics for auditory and visual material, even when the stimuli are matched in term of discriminability, and are designed to undergo very similar transformations when they are encoded and retrieved from memory.
The concept consists of a matrix of small flaps (rigidly fixed at their upstream end and covering an enclosed cavity) which are designed to undergo aeroelastic deflection to achieve proper mass bleed or injection when subjected to gas dynamic shock loads.
These prodrugs are designed to undergo intracellular activation to generate unstable phosphoramidate anion intermediate B, which in turn undergoes spontaneous cyclization and P N bond cleavage by water to liberate the nucleoside monophosphate.
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They were designed to undergo an enzymatic activation followed by a self-cleavage to release a parent drug.
The test specimen was designed to undergo joint shear failure prior to flexural yielding of the connected SC walls.
The proposal was designed to undergo few adaptations in case of expansions to other networks, but it is necessary to consider the constrains, such as permissions and ways of information extraction.
In addition, self-assembled prodrug hydrogels can be designed to undergo controlled drug release or tailored degradation in response to biological cues.
We introduce a liquid metallurgy synthesized, non-equiatomic Fe40Mn40Co10Cr10 high entropy alloy that is designed to undergo mechanically-induced twinning upon deformation at room temperature.
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