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Cancer cells are more sensitive to radiation than are healthy cells because they are continuously proliferating.
Cancer cells are continuously proliferating, and this uncontrolled growth is mediated by the activation of different signal transduction pathways that ultimately lead to the carcinogenic process.
The central brain neuroblasts are continuously proliferating during the third larval instar (Ito and Hotta, 1992), and so we used this stage to determine whether transient Prospero expression could induce neuroblast quiescence.
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The p16-positive cells do not cycle and are continuously diluted as the cultures proliferate, while new p16-positive cells are generated in the cultures from proliferating cells, thus maintaining a steady-state frequency of p16-positive cells of approximately 20%.
Epithelial cells in the breast do not proliferate greatly and are continuously being replaced and thus they do not have a considerable opportunity to be the target of mutation events.
The cells in body column proliferate and are continuously displaced towards hypostome and foot.
All three methods are sensitive to replication (Okayasu et al, 1988; Stamato and Denko, 1990; Iliakis et al, 1991a, 1991b; Dahm-Daphi and Dikomey, 1995), which might be important for continuously proliferating tumour cells.
Finally, the adult stratified epidermis is characterized by a homeostatic process where self-renewing stem cells residing in the basal layer proliferate to replace interior cells while exterior cells are continuously lost to the outside environment.
Furthermore, the melanocytes are highly sensitive to apoptosis caused by chemical signals caused by bacterial toxins, microtubule structure damaging substances, or protein synthesis inhibitors [ 37]; therefore, their reduction must be complemented by continuously proliferating cells.
The surface of palatine tonsil is covered by a stratified squamous epithelium where the most external cells are continuously lost by sloughing and replaced by cells that are displaced upwards from the proliferating suprabasal cell layers.
These are continuously diploid.
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