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Patients whose disease never cleared after treatment are considered recurrent with a recurrence time = 1 day.
For purposes of training and validating the algorithms discussed in this paper, patients for which cancer recurred within 3 years (of surgery) are considered recurrent (high risk) and those that had recurrent cancer, or survived without recurrence beyond 3 years, are considered non-recurrent (low risk).
Key symptoms leading to surgery are considered recurrent giving-way episodes during daily activities, which affect the quality of life of the subject.
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Likewise, setting the radius too small would cause very few points to be considered recurrent.
Setting the radius too large diminishes the sensitivity of the analysis, because many (or in the extreme case all) points would be considered recurrent.
Cases were considered recurrent only when at least one week without symptoms fell between episodes.
Patients for which cancer recurred within 5 years of surgery were considered recurrent (high risk).
AF is considered recurrent when a patient develops two or more episodes.
Copy number gains or losses were considered recurrent if present in > 50% of the CTC samples from 9 patients.
NFE2L2 mutations within the TCGA UCEC dataset would not be considered "recurrent mutations", as they are present only between one to three times at any one site.
The MSD was considered recurrent when the conscript has previously sustained an MSD of the same type and in the same location [ 17, 18].
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