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There are considerable difficulties in identifying whether certain disabilities (e.g., deafness or arthritis) arise from work, and there are instances in which an injury is only partially attributable to the work situation.
There are considerable difficulties in designing future efficacy trials, some related to the field of ALS and some that are specific to SCs or the mode of delivery.
There are considerable difficulties in designing future efficacy trials, some being generic to the field of regenerative treatment in stroke, and some that are specific to stem cells or their mode of delivery.
Although there are considerable difficulties in the experimental and computational detection of protein interactions in Plasmodium that can lead to artefactual observations, we nevertheless find strong biological significance in the obtained rich-club phenomenon in the interactome of Plasmodium, results that potentially can point to a topological signature of a parasite specific life style.
It could also potentially be applied to the cryopreservation of other reproductive or even major organs (kidneys) where there are considerable difficulties in storing donated tissue.
However, there are considerable difficulties in diagnosing adult ADHD, mainly because of high comorbidity rates and uncertainty in the recall of childhood symptoms by potential ADHD patients and their parents.
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He also warned him that there were "considerable difficulties" in justifying the use of force on self-defence grounds.
There have been considerable difficulties in recent years in recruiting and retaining paediatricians and social workers working at the very sharp-end of child protection.
In Haiti, there were considerable difficulties in gaining an overview of HRH, their capacity and their gaps due to an inadequate health workforce information system, currently under revision.
But in fact he holds that there is considerable difficulty in making sense of the doctrine.
However, there has been considerable difficulty in developing an efficacious malaria vaccine, highlighting our incomplete understanding of immunity against this disease.
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