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The majority of studies on miRNAs and the brain have been carried out on miRNAs that are conserved during evolution, and the conservation of miRNA target in the mRNA 3′-untranslated region (UTR) is used as a criterion in assessing potential miRNA actions on a gene.
Remarkably, miRNAs sequences, their expression patterns, and sequences of respective RNA targets are conserved during evolution, suggesting the ancient origin and the crucial function of miRNAs in conserved developmental processes.
As all of the methods may alter the proteins' structure and function, it is important to verify if the functions are conserved during the treatments of the cells.
MRG proteins are conserved during evolution in fungi, flies, mammals and plants, and they can exhibit diversified functions.
By assuming a completely inelastic collision at landing (Fig. 6), the object's angle and its angular velocity in the horizontal direction are conserved during the collision, and the angular velocity in the vertical direction dissipates.
Because inclinations of dust particles are conserved during the orbital evolution under the P-R effect, ī is identical to the average inclination of EKBOs, namely, ī ∼ 0.1 (e.g., Noll et al., 2008).
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SDS PAGE analysis revealed that the protein molecular weight was conserved during fibre spinning.
This molecular information can be conserved during reactions catalysed by selective organocatalysts.
These results demonstrate that although the protein-DNA contacts made by the Myb repeats have been conserved during the evolution of animals, the protein-protein interactions have diverged.
Meanwhile, restriction digestion and gene sequencing analyses demonstrated that the pcDNA-CCOL2A1 vector remained stable, and that the plasmid sequence was conserved during this period.
Expression of transcription factor genes (RIN43, TAGL1 (ref. 44) and NOR45) and genes involved in ethylene signaling pathways (NR46, ETR4 (ref. 47), EIN2 (ref. 48) and EIL families49) was conserved during fruit ripening (Fig. 4).
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