The role of TGFβ in cancer is complex and ranges from cell growth inhibition to regulation of cell migration and invasion [ 6, 9, 10].
The factors influencing food prices are complex and multiple, ranging from extreme weather conditions to export bans and rising supply and demand from emerging markets".
But the joint mechanisms are complex and the motion range is small.
The causes of suicide are complex and include a range of factors, not all of which are always apparent.
In addition, sponsors of most newly approved drugs will be required to conduct postapproval CV outcome studies (12), which are complex and expensive; at a range of 20,000 40,000 USD/patient, these trials reach costs of ≥250 million USD.
The root causes of under-representation are complex and a much wider range of factors need to be taken into account to fully understand the problem," Piatt said.
The links between the weathering of silicate minerals, the global carbon cycle and climate change are complex and involve a whole range of often inter-related tectonic, climatic, geomorphological and biological factors.
ICT implementations in healthcare delivery systems are complex and influenced by a range of factors at individual and organisational levels.
However, MRI studies are complex and have a new range of variables, including different imaging sequences, protocols and hardware, but quantification is improving, allowing for a good level of accuracy and reliability in measurements of cartilage volume and thickness [ 28].
This broader view might result from the fact that the tests applied for assessing executive functioning are complex and induce a wide range of skills, thus complicating efforts to identify a unitary interpretation framework [ 37].
