Exact(7)
The BT mice differ from the Ar-KO mice in that the Ar-KO mice are completely deficient in AR whereas the BT mice are deficient in AR in all tissues, including most parts of the kidney, except the medullary collecting tubule epithelial cells that carry the knockin transgene.
These individuals are completely deficient in BuChE but have only minor abnormalities in clinical test results [34], [35].
This gene encodes a key hemeoxygenase enzyme involved in phytochrome chromophore biosynthesis; therefore, se5 mutants are completely deficient in their photoperiod response and in spectrophotometrically detectable phytochromes [11].
Second, because the PS2 KO cells are germline knockout and are completely deficient in PS2 compared to partial knockdown of PS2 in cell lines, the two cell types are not complete parallels.
We recently reported that mice that are completely deficient in TANK2 expression [18], or mice that express only a mutated form of TANK2 lacking PARP activity [6], manifest similar phenotypes with limited differences from wild type controls.
As to the first, transgenic mice that are completely deficient in muscle CK lack burst activity (van Deursen et al. 1993).
Similar(53)
It's not that the American health system is completely deficient in small, clever, inexpensive fixes.
Muhamed Haneef, for example, was accused of engaging in terrorist activities, the evidence of which the Clarke Inquiry found to be "completely deficient".
Furthermore, an L. monocytogenes mutant in the Internalin A gene is completely deficient in attachment to the epithelial apical surface and is unable to invade.
We confirmed that CAG MnSOD knockout mice were completely deficient in MnSOD and died as neonates, validating the use of the Cre loxp system.
Cells co-expressing Prv-1 and an Mpl receptor containing a Box 1 motif mutation, which fails to activate Jak2, was completely deficient in Tpo-dependent proliferation.
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