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The supposedly troublesome characteristics of the pit-bull type — its gameness, its determination, its insensitivity to pain — are chiefly directed toward other dogs.
Given that amino acids are chiefly directed into proteins, this suggests that the cell has developed more complex methods to regulate proteins post-transcriptionally than sterols and the entry point into phospholipid biosynthesis.
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The assembly of monomers into supramolecular architectures via non-covalent interactions is chiefly directed by the molecular structures, their functional groups, and environmental conditions.
The stress transfer mechanism is formulated from a microscopic point of view, and the engineering attention is chiefly directed at coupled cyclic pullout and transverse shear.
The great pre-Reformation wave of discontent in Europe was chiefly directed at the corrupt worldliness of the Catholic church, but it also had a political target.
After New York Magazine's Michael Idov read The Nurse and the Novelist, a nifty piece of satire by Russian émigré Anya Ulinich, he assumed the not-so-gentle send-up of "a straw man of an American writer making a fortune off whimsical novels about Soviet Jews" was chiefly directed at Foer.
That program was chiefly directed at freeing churches from lay control, especially by the appointment of unworthy candidates to ecclesiastical office through simony (i.e., the practice of buying church offices), and at forbidding the pervasive practice of clerical marriage and concubinage, which threatened the substance of the church.
These are chiefly in music.
They are chiefly influenced by blowing winds.
They are chiefly aimed at domestic consumption.
The issues presented are chiefly of law.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com