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The phrase "are chiefly affected" is correct and usable in written English.
It can be used to describe the primary impact or influence on a particular group or situation.
Example: "The new policy changes are chiefly affected by the recent economic downturn, leading to significant adjustments in budget allocations."
Alternatives: "are primarily impacted" or "are mainly influenced".
Dictionary
are chiefly affected
adverb
Especially or primarily; above all
Similar(60)
The next step will be to determine how and why they caught these bacteria and why young seals have been chiefly affected.
However, when the temperature was over 600 °C, the results were chiefly affected by sintering effects.
In turn, densityNV variation was chiefly affected by fibre wall and lumen fractions.
For participant P5, however, the error in perceived direction was chiefly affected by lateral distance, with larger rightward errors for head positions H2 and H4.
Blood and plasma viscosity are the major factors affecting blood flow and normal circulation, so the whole blood viscosity is chiefly affected by plasma viscosity, red blood cell deformability, hematocrit, and other physiological factors.
To begin with DDT, its action in man is primarily on the central nervous system; the cerebellum and the higher motor cortex are thought to be the areas chiefly affected.
Dopamine-producing neurons are the ones chiefly affected in Parkinson's.
They are chiefly influenced by blowing winds.
These are chiefly in music.
They are chiefly aimed at domestic consumption.
They are worldwide in distribution but are chiefly tropical.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com