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Because DT40 cells are capable of proliferating faster than any mammalian cell line, larger numbers of cumulative cellular proliferation can be measured over a limited time for high-throughput screening.
However, a subpopulation termed variant HMECs are capable of proliferating for an additional 30 50 generations, and reach a plateau of high proliferation and high apoptosis termed agonescence in which the cell population does not increase but sustains itself.
Moreover, after cell processing, the CD45RA-depleted PBSC products are enriched for CD4+ and CD8+ TM with a central memory phenotype and contain TM cells that are capable of proliferating and producing effector cytokines in response to opportunistic pathogens.
Transposable elements are genetic elements that are capable of proliferating within and even between genomes.
In contrast to terminally differentiated osteoclasts, monocytes are capable of proliferating in the culture, and they die primarily by apoptosis.
CD4+6.5+CD25− cells from dtg mice, which represent the majority of the FoxP3− population, can be considered as T conventional (Tconv) cells, because they are capable of proliferating and secreting IFNγ in response to various peptide doses and, in contrast to their CD25+ counterparts, do not suppress proliferation of 6.5+CD25− cells from stg mice (Fig. 1B).
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The co-staining of ERα and Ki-67 suggests that ERα-positive cells in these primary breast tumors might be capable of proliferating, i.e., ERα might be able to mediate cell proliferation via autocrine fashion in these primary breast tumor cells.
The two strains showed different profiles: (A) strains that resisted the bactericidal action of the serum and were capable of proliferating, and (B) other strains that showed sensitivity to the serum and of which the percentage of survival decreased.
The cell lines we obtained were capable of proliferating stably on the vole feeder layer, in the absence of LIF, without changes in morphology (see Table 1).
Remarkably, all of the cancer cell lines examined in this study were capable of proliferating on soft substrates, whereas normal fibroblasts, smooth muscle and epithelial cells exhibit a strict dependence on matrix rigidity for growth [25].
MDSC do not fuse quickly with each other and have been shown to be capable of proliferating more efficiently.
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