Many nutrients are capable of modulating the immune system.
Exosome-shuttled molecules maintain their biological activity and are capable of modulating and reprogramming recipient cells.
Prior work has shown that young, healthy people are capable of modulating arm stiffness via selective muscle co-contraction to account for external disturbances in various directions.
Following activation, spinal microglia proliferate and release many substances which are capable of modulating neuronal excitability within the spinal cord.
These results demonstrate that engineered ZFP-TFs comprised of plant-derived elements are capable of modulating the expression of endogenous genes in plants.
In addition, we demonstrate that IL-18-secreting CAR T cells are capable of modulating the tumor microenvironment, as well as enhancing an effective endogenous anti-tumor immune response.
Using neuropathic pain as an example, this article reviews current knowledge of the structure and function of ion channels and current technology and future opportunities for the identification of novel drugs that are capable of modulating ion channel function.
It is long-recognised that bacteria (and indeed other pathogens) belonging to genetically distinct phyla are capable of modulating the repertoire of co-stimulatory and co-inhibitory molecules expressed on the APC surface23, thus affirming the critical importance of said receptors in the directing of adaptive immune responses.
In summary, we have demonstrated the existence of physiologically activated presynaptic ionotropic glutamate receptors that are capable of modulating levels of intracellular calcium and have highlighted the importance of receptor-mediated increases in postsynaptic calcium for neuronal plasticity in the lamprey.
Protease-degradable hydrogels obtained by photoinitiated thiol-norbornene click chemistry are rapidly formed in the presence of dermal fibroblasts, exhibit tunable properties and are capable of modulating the behavior of embedded cells, including the cell spreading, hydrogel contraction and secretion of matrix metalloproteases.
Astrocytes are capable of modulating NMDAR activity through glutamate uptake transporters [121].
