This is necessary to protect cells from sudden increases or decreases in water content, which are capable of interfering with proper cell function.
As outlined above, recent reports have shown that a number of xenobiotics in the environment are capable of interfering with the normal endocrine function in a variety of animals.
To evaluate intraovarian dominance effects in a sheep model and to determine whether local factors, independent of FSH-mediated pathways, are capable of interfering with the final development of subordinate follicles.
Since multiple binding sites for LAIR-1 and LAIR-2 are present on both human collagens I and III [10], we hypothesized that soluble LAIR proteins are capable of interfering with collagen-platelet interactions.
Thus, a population of IFNγ-secreting T cells are provided that are capable of interfering with the liver stage of the life cycle, thus reducing or preventing merozoite release.
Many of these chemicals are capable of interfering with endocrine signaling via a complex array of biomolecules (e.g., hormones) to regulate processes such as reproduction and metabolism.
Some pathogens are capable of interfering with differentiation in order to down-regulate the anti-microbial activity and enhance their survival in the host.
For example, bloodstream T. cruzi trypomastigotes express molecules on their surface that are capable of interfering with the activation of the classical and alternative complement pathways [ 147].
To that end, Haass and Selkoe [ 11] have recently evaluated the concept that soluble oligomers of Aβ, acting as diffusible assemblies, are capable of interfering with synaptic function and integrity.
Furthermore, in vitro studies have shown that Aβ42 aggregation is inhibited by Aβ40 [ 40- 42], and also by Aβ37 and Aβ38 [ 43], suggesting that the shorter peptides are capable of interfering with the amyloid cascade.
