Because there are no routine screening tests and few markers to identify groups with increased risk of ovarian cancers, most cases are found when they are beyond the point of curing.
A large majority of patients present with advanced disease that is beyond the scope of cure, and even after surgical resection with curative intent more than 50%% of patients will develop recurrence and/or distant metastases [ 3].
The large majority of patients present with disease that is beyond the scope of surgical cure, and their clinical course is characterised by debilitating symptoms and an extremely poor prognosis (Schnall et al, 1996).
We observed and digitally recorded 37 oncology consultations (three patients were too ill to keep the appointment with the oncologist; two consultations were not recorded; one patient refused to see an oncologist; and the possibility of cure, judged to be beyond the definition of survival benefit for this paper, was mentioned during two consultations).
Some selected cure rate models are reported in Table 2. Further detail is beyond the scope of the paper.
"It's beyond the political".
However, the development of distant metastasis still means that the patient is beyond cure (Clarke et al, 2005; Early Breast Cancer Trialists Collaborative Groupp, 2005; Verdecchia et al, 2007; Liu et al, 2010).
Since we were interested in factors, which can predict whether the tumour is beyond cure by surgery alone, we reasoned that especially molecules involved in cell cell and cell extracellular matrix (ECM) interactions might be of high relevance.
Tarkovsky died of cancer at the end of 1986, and there are gentle scenes of the sick man greeting his family, who were generously permitted to join him in France when the Soviets were satisfied that he was beyond cure.
Then by the time it is diagnosed, it can be beyond a surgical cure".
