The phrase "are best established" is correct and usable in written English.
It can be used when discussing the optimal conditions or methods for establishing something, often in a formal or academic context.
Example: "The principles of effective communication are best established through consistent practice and feedback."
Alternatives: "are most effectively established" or "are ideally established".
Boundaries are best established during the job interview, Ms. Duncan said.
Every relationship has different rules and expectations that are best established at the beginning, rather than building on a foundation of distrust and resentment.
Trust networks are best established with physical and unstructured interaction, discussion and observation.
Although calibration and validation sets are best established using experimental designs, industrial laboratories cannot afford such an approach.
Ideally, health needs are best established through sound population-based epidemiological data.
And beyond that, the credibility of a higher inflation target in the face of the deflationary bias of central bankers may well be best established by (a) reducing the central bank's autonomy and (b) getting the central bank in the business of supporting — indeed, monetizing — government deficits, at least for a while.
Current knowledge is best established at Mount Meager north of Mount Garibaldi and is likely to rise considerably with a temporary mapping and monitoring project.
Current knowledge is best established at Mount Meager and is likely to rise considerably with a temporary mapping and monitoring project.
Current knowledge is best established at Mount Meager in the Garibaldi Volcanic Belt of southwestern British Columbia and is likely to rise considerably with a temporary mapping and monitoring project.
The connection between RNA silencing and chromatin is best established for Schizosaccharomyces pombe and plants where chromatin-associated silencing complexes were extensively characterized (reviewed in [1], [2]).
On the other hand, if the gene family members are found only in animals, phylogeny is best established by including other closely related gene families in the dataset.
