In other cases, particularly in most prostate cancer metastases, lesions are prone to be osteoblastic, forming more bone tissue than that is being resorbed.
However, ovary dissections at 48 h post bloodmeal showed a greater number of more developed follicles suggesting that fewer of the vitellogenic follicles were being resorbed.
Of particular interest is the determination of whether new bone is forming or whether pre-existing bone is being resorbed in response to the altered patterns of stress that are created by the components.
This difference is particularly evident in OA because different parts of the skeleton or even different areas within the same bone experience reverse metabolism, e.g., subchondral bone undergoes osteosclerosis and forms osteophytes while cancellous bone at the metaphysis is being resorbed.
Most females have a single functional ovary (on the left side), though some have two; the oviducts are often filled with yolk, which has been speculated to be from unfertilized eggs being resorbed.
At E19 some of these mice were recovered alive by Caesarean section and established regular breathing, some failed to establish normal breathing, some appeared edematous and were not recovered alive, whilst others were in the process of being resorbed from earlier embryonic lethality.
In many cases of skeletal metastasis, particularly from breast and lung cancers, the lesions are prone to be osteolytic, resorbing more bone tissue than that is being formed.
HA is considered osteoconductive and non-resorbable, whereas β-TCP is osteoconductive but is resorbed quickly [8 11], because calcium and phosphate ions released from β-TCP during degradation are used to form new tissue, and the resorption of β-TCP provides space for new bone formation.
HA until recently was considered to be non able to be resorbed.
The presence of residual stress can cause failure or even change the dissolution rates of many materials, in particular biomaterials that are designed to be resorbed.
