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To enable future comparison of results, all interventions are being evaluated using the same Assessing Cost-Effectiveness (ACE) method of economic evaluation [15].
Participants' experiences and views regarding the StepUp program are being evaluated using a purpose-designed feedback survey (Additional file 1).
Maternal and infant outcomes in all groups are being evaluated using age-appropriate questionnaires completed when infants are aged <2 months (pre-intervention), 9, 15 and 21 months.
Patients will follow the care to which their practice is randomised with identical participant information for both arms explaining that their local musculoskeletal services are being evaluated using patient self-complete questionnaires and medical record review.
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It is being evaluated using the Medical Research Council's framework for the evaluation of complex interventions.
The fracture process is being evaluated using the combination of AE and Digital Image Correlations (DIC) techniques.
Depression in patients is being evaluated using the seven-item questionnaire of the Center for Epidemiologic Studies Depression (CES-D) scale.
The Breathlessness Intervention Service (BIS) Service at Addenbrooke's NHS Trust is being evaluated using the MRC framework [ 6].
Educational achievement is being evaluated using the results from the standardized tests at completion of the 9th grade and the status at age 22 years.
LEAP is being evaluated using a quasi-experimental design with measurements taken at -6, 0 (baseline immediately pre-intervention), 6 and 12 months.
The efficacy of natural products (NPs) is being evaluated using randomized controlled trials (RCTs) with increasing frequency, yet a search of the literature did not identify a widely accepted critical appraisal instrument developed specifically for use with NPs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com