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Interestingly, the studied compound has electron deficient bivalent sulphur atoms (~ + 0.4769) have relatively low-lying σ*-orbitals (0.209-0.235 A.U). related to the C-S bonds that are available for interaction with the electron donor O-atoms neighboring to them.
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On the basis of the details of the formation of various complexes in a wide range of CBP and pRb concentrations, it has been concluded that E1A CBP pRb interactions might display positive or negative cooperativity, depending on which domains of E1A are available for interaction with CBP/p300 and pRb.
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Recent crystallographic and NMR studies of truncated human αB crystallin core-domains suggest that the 113FISREFHR120 sequence may be involved in dimerization [38], [45] through hydrogen bonds of the backbone while the F113, S115, E117, H119 side chains are exposed on the surface of the αB crystallin complex and are available for interactions with tubulin.
The silver ions may be available for interaction with other molecules.
The 5-HT1D receptors are localized in fact in trigeminal primary afferent nociceptors, in dense core vescicles, which suggests that they would be available for interaction with triptan only with nociceptive stimulation of sufficient intensity [29].
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The structural data are consistent with biochemical and computational data indicating that the 113FISREFHR120 sequence is not involved in subunit-subunit interactions and is available for interaction with target proteins [15], [37], [50].
Therefore, FOG-2 is available for interaction with GATA factors.
This implicates that the N-terminus of none of these proteins is available for interaction.
However, the opposite face of the protein is available for interaction and is predicted to have a structure very similar to that of SAS-6.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com