Intriguingly, polymorphisms of this receptor are associated with SLE, although their precise role in the disease and potential for targeted therapeutic intervention is not understood.
Although, our data suggest that IL-6 levels in ascites are associated with shorter progression-free survival, the precise underlying molecular mechanisms responsible for these findings remain to be established.
Although, both the existence of this syndrome, its precise definition, and its prognostic relevance have been hotly debated in recent years, it is clear that combinations of risk factors are associated with poorer outcomes [ 6- 8] yet the precise nature of these interactions and associations among risks factors remains moot [ 9- 11].
Many proteins are associated with human diseases, although very often their precise functional role in disease pathogenesis remains unclear.
Although there is consensus that morning BP surges are associated with cardiovascular events, no consensus on their precise definition has been reached as yet 30.
Data from our previous studies suggest that breast cancer cells that show low expression of DJ-1 proteins are associated with DJ-1 protein secretion, although the precise mechanism for downregulation of the DJ-1 protein remains unclear.
Compounds of EPSCs with τrise/τdecay of 0.1/1, 0.3/3 and 0.6/6 ms induced rapid transitions of the somatic membrane potential, and were associated with temporally precise spike responses with Δt<2.45 ms (mean = 1.35 ms, s.e.m. = 0.30 ms).
The use of aseptic, cGMP-compliant P. falciparum-infected mosquitoes is safe, is associated with a precise prepatent period compared to the standard model and appears more efficient than the standard approach, as it led to infection in 100% (6/6) of volunteers exposed to three mosquito bites and 83% (5/6) of volunteers exposed to one mosquito bite.
Although comparative genomic hybridization studies have revealed gains in distal segments of 17q in some tumors, including prostate cancer [ 31, 32], they have not been associated with the precise region in 17q25.3 described in our study.
