Among the members of the order that have attracted special attention are certain kingfishers that plunge headfirst into water for fish and are associated with Classical mythology; according to the ancient Greeks, Ceyx and his wife Alcyone were shipwrecked at Delphi and were changed into kingfishers.
Glutamatergic systems are also implicated by identification of "druggable" metabotropic 7, GRIK2 kainate and GRIA4 AMPA glutamate receptors, as well as several cell adhesion molecules that are associated with classical synapses.
PIK3CA mutations are associated with classical markers of good prognosis and signatures of PI3K pathway activity.
XR9051 was able to reverse resistance to a variety of cytotoxic drugs, including doxorubicin, etoposide and vincristine, which are associated with classical MDR.
Mutations in the zinc-binding loop and the zinc-binding sites, such as G72C (Stewart et al., 2006), D76Y (Andersen et al., 1997) and H80A (Alexander et al., 2002), are associated with classical ALS phenotypes.
Four of these alleles are associated with classical DOA (G300E, N728K, Q785R, L939), whereas the other four (G439V, S545R, R445H, V910D) are associated with the more severe form termed 'OPA1 plus' DOA, which includes multiple mtDNA deletions in addition to the classical optic atrophy (17, 18).
Opera is associated with classical music and its style of singing, where the voice and the notes are more important than the text.
The haplotype includes insertion alleles at the 23 and 12-bp indels which have previously been shown to be associated with classical BSE [14] [17].
Within the control group and the combined groups, measures of vascular function and structure were associated with classical risk factors for atherosclerosis, most strongly with age and systolic blood pressure.
